Protein Modification Reagents
AG Scientific Inc Dithiothreitol, DTT, 5 G
Dithiothreitol (DTT), is a small-molecule redox reagent, known as Cleland's reagent, that forms a six-member ring with an internal disulfide bond. It has a redox potential of -0.33 V at pH 7. The reduction of typical disulfide bond proceeds by two sequential thiol-disulfide exchange reactions.DTT is effective in buffers to reduce protein disulfide bonds prior to SDS-PAGE. It can protect protein sulfhydryls and restore enzyme activity lost by oxidation.CAS Number: 3483-12-3Molecular Weight: 154.2Chemical Formula: C4H10O2S2Solubility: 10% solution in water. Clear and colorlessStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.
Ubpbio TCEP Powder, 10 GR, CAS# 51805-45-9
Reducing Agents - TCEP - TCEP (tris(2-carboxyethyl)phosphine) is a strong reducing agent. Compared to dithiothreitol (DTT) and β-mercaptoethanol, TCEP has the advantages of being odorless, a more powerful reducing agent, an irreversible reducing agent, more hydrophilic, and more resistant to oxidation in air. It is soluble in water and stable at neutral pH. It does not reduce metals used in immobilized metal affinity chromatography such as Ni-NTA resin. TCEP is particularly useful when labeling cysteine residues with maleimides.
Cayman Chemical DL-DIthIothreItol 10g
A reducing agent; has been used to stabilize thiols in a reduced state in various applications, including protein purification and enzymatic assays
Cayman Chemical TCEP-botn 1mg
An affinity probe for protein lysine crotonylation; addition of the TCEP moiety to crotonylated lysine residues results in adduct formation that allows for detection or immobilization of crotonylated proteins through interaction with the biotin ligand; has been used in the detection and isolation of crotonylated histones in HEK293 cells
Ubpbio TCEP Powder, 25 GR, CAS# 51805-45-9
Reducing Agents - TCEP - TCEP (tris(2-carboxyethyl)phosphine) is a strong reducing agent. Compared to dithiothreitol (DTT) and β-mercaptoethanol, TCEP has the advantages of being odorless, a more powerful reducing agent, an irreversible reducing agent, more hydrophilic, and more resistant to oxidation in air. It is soluble in water and stable at neutral pH. It does not reduce metals used in immobilized metal affinity chromatography such as Ni-NTA resin. TCEP is particularly useful when labeling cysteine residues with maleimides.
Biotium TCEP
TCEP (Tris(2-carboxyethyl)phosphine) hydrochloride is an odorless reducing agent that is more stable and effective than dithiothreitol (DTT) or 2-Mercaptoethanol. TCEP hydrochloride is soluble in water to 310 grams per liter. Unlike DTT, TCEP hydrochloride retains its reducing power at acid pH (pH 5) and at pH above 7.5. TCEP hydrochloride is unreactive towards other functional groups found in proteins. For reducing disulfide bonds in peptides or proteins, 5-50 mM TCEP can be used for a few minutes at room temperature.Properties: C9H15O6P HCl; Mwt: 286.64; [51805-45-9].
Bachem Fmoc-OSu
Fmoc-OSu, 82911-69-1, C19H15NO5, Mr 337.33, 25g. N-(9-Fluorenylmethyloxycarbonyloxy)-succinimide. Most efficient reagent for the selective preparation of Fmoc-derivatives of hydroxy amino acids in high yield. The advantage of Fmoc-OSu is that little or no oligopeptides are formed when amino acid derivatives are prepared. The use of this reagent in the synthesis of glycopeptides has been reported as well.
Medchemexpress LLC PROTAC ATR degrader-2 | 3010273-12-5 | 99.7% | 743.81 | 5 MG
PROTAC ATR degrader-2 | 3010273-12-5 | 99.7% | 743.81 | 5 MG
Medchemexpress LLC Protac MDM2 degrader-1 | 2249944-98-5 | MFCD32197288 | 98.1% | 1463.33 | C74H84Cl4N10O13 | 5 MG
PROTAC MDM2 Degrader-1 is a research-grade PROTAC designed to target MDM2 for induced degradation and p53 modulation in cell-based studies. It is supplied as a high-purity solid in small milligram quantities for preclinical research.
- Small-molecule PROTAC that induces MDM2 degradation for research use.
- High purity: 98.1%.
- Molecular weight: 1463.33 Da; formula: C74H84Cl4N10O13.
- Appearance: solid, supplied in milligram quantities.
- Storage: store under nitrogen; in solvent -80°C (6 months) or -20°C (1 month).
- Available package sizes: 1 mg, 5 mg, 10 mg, 25 mg; larger sizes by quote.
AdipoGen Guanidine hydrochloride
Chemical. CAS 50-01-1. Formula CH5N3 . HCl. MW 59.07 . 36.46. Guanidine hydrochloride is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids. It is useful for denaturation and refolding of proteins as well as in the recovery of periplasmic proteins. At higher concentrations, this strong denaturant has been reported to solubilize denatured insoluble proteins such as inclusion bodies and to increase the solubility of hydrophobic molecules. When utilized at lower concentrations, it is useful in prompting the refolding of denatured proteins. Guanidine hydrochloride is also been reported to allow return of enzymatic activity in protocols using it as a first step. Guanidine hydrochloride is used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
United States Biological Corporation GUANIDINE HYDROCHLRD 8M 100ML
NC3844811 GUANIDINE HYDROCHLRD 8M 100ML